Endocrine Abstracts

Stem cell therapy for haematological disorders is a longstanding successful procedure. Over the past few years it has been realised that stem cells originate from tissues other than bone marrow and it is generally accepted that these cells and products derived from them offer the possibility of new treatment for many diverse conditions. Currently the relative therapeutic benefits of stem cells obtained from embryos, fetal cord blood, bone marrow or other tissues have yet to be...

Activation of the hypothalamo-pituitary-gonadal axis, from the third trimester of pregnancy to the first post-natal months in males, results in serum concentrations of gonadotrophins and testosterone approaching adult levels. This phase, known as male mini-puberty, represents a key window of opportunity to identify congenital GnRH deficiency in early childhood.We present a case to illustrate the diagnostic efficiency of screening for mini-puberty in a ma...